Dr. Guella is a human molecular geneticist whose research interests are primarily directed at understanding how genetic variability acts on neurodegenerative diseases. She graduated from the University of Milan, Italy in 2006 with a M.S. degree in Medical Biotechnologies and Molecular Medicine, and in 2009, Dr. Guella completed her PhD in Molecular and Cellular Biology at the University of Milan, Italy. Her PhD research was focused on understanding the underlying genetic basis of complex disorders such as cardiovascular diseases and Parkinson’s Disease (PD).
In 2011, Dr. Guella worked as a postdoctoral research fellow at the Department of Psychiatry and Human Behavior at the University of California, Irvine, investigating the molecular and genetic basis of psychiatric disorders.
Presently, Dr. Guella is seeking to apply her experience and training in human genetics and molecular biology to the field of neurodegenerative disorders, which has continued to fascinate her. Her main focus is on elucidating genetic variability that either causes or contributes to the onset of neurologic and neurodegenerative disease, using state-of-the-art approaches, which range from classical linkage, genome-wide genotyping, through next-generation sequencing. Dr. Guella uses these technologies to understand how genomic variability impacts the onset and course of PD by studying multi-incident families, with two or more affected family members, and extensive sample collections of idiopathic PD cases and controls.
The long-term goal is to elucidate the genetic basis of neurodegenerative diseases, with the overall goal of identifying new molecular pathways that could contribute to develop successful therapies.